Health Update: Artificial Sweeteners Harmless?? Ask Your Gut!!

RVAchironeuro • September 26, 2022

09.26.22

 

Hello again everyone:

Here is a new article that reveals how artificial sweeteners can damage our health. It appears that the artificial sweeteners alter our gut microbiome that then has a negative influence on blood sugar control which induces insulin resistance. This is not a good or health building result as insulin resistance causes or leads to: type 2 diabetes; weight gain; inflammation; cardiovascular disease; high blood pressure; kidney damage; nerve damage; dementia; brain fog and more. Here is what one study said:

Results: The HOMAIR values for Group A and B ranged from 0.9–24.33 and 0.12–10.83 with mean values 7.39 and 2.6, respectively, showing that the ones who used AS had a higher insulin resistance. The study also showed that the duration of use of artificial sweeteners had a direct impact on insulin resistance.

It turns out that there are a lot of studies on this topic. You can click on these links to read more if you are interested. Here is a summary from the link immediately below:                                                                                                                                                                                           “Non-nutritive sweeteners (NNS) are commonly integrated into human diet and presumed to be inert; however, animal studies suggest that they may impact the microbiome and downstream glycemic responses. We causally assessed NNS impacts in humans and their microbiomes in a randomized-controlled trial encompassing 120 healthy adults, administered saccharin, sucralose, aspartame, and stevia sachets for 2 weeks in doses lower than the acceptable daily intake, compared with controls receiving sachet-contained vehicle glucose or no supplement. As groups, each administered NNS distinctly altered stool and oral microbiome and plasma metabolome, whereas saccharin and sucralose significantly impaired glycemic responses. Importantly, gnotobiotic mice conventionalized with microbiomes from multiple top and bottom responders of each of the four NNS-supplemented groups featured glycemic responses largely reflecting those noted in respective human donors, which were preempted by distinct microbial signals, as exemplified by sucralose. Collectively, human NNS consumption may induce person-specific, microbiome-dependent glycemic alterations, necessitating future assessment of clinical implications.

Bottom Line: There is no compelling reason to consume non-nutritive artificial sweeteners as they clearly appear to negatively affect our health. They are shown to harm our vital microbiome which can lead to insulin resistance and many other poor health outcomes. Overall and for most of us, the less ‘sweetness’ the better, thus limiting consumption of processed foods and reducing any added sweeteners of most any type will offer a boost to your health.

 

By Mark Smith March 23, 2026
Health News Update: How To Fight Inflammation and Chronic Disease 3.23.26 Hello again everyone: You might wonder why I keep focusing on food…so here are some of the reasons: food choices are the leading cause of death in the U.S. and spreading around the world. Poor food choices lead to inflammation which slowly destroy health. It is that simple, plain, and clear and backed by research. The next question: how do we fight back? Introduction The positive impact of food on health was postulated by the ancient Hippocrates, father of modern medicine with his famous quote: “Let food be thy medicine and medicine be thy food” [1]. In the 21st century, scientists have focused on the effect of nutritional habits in diseases. Nowadays, it is well documented that food plays a noteworthy role in the pathogenesis of chronic diseases namely cardiovascular diseases (CVD), metabolic syndrome, diabetes mellitus type II, and cancer [2–5], as it correlates with others with the lipid pattern, the blood pressure, and the endothelial function. The scientists examine the effect of nutritional habits on disease emergence and progression in both individual nutrient intake and dietary patterns models. Worldwide, two dietary patterns are usually compared—the Mediterranean diet (MD) and the Western diet (WD) [3,6]. The Mediterranean diet reflects the food culture of most Mediterranean countries based on olive oil consumption, seasonal fresh vegetables, cereals, and plants in balance with low consumption of meat [7]. The Western diet, on the contrary, is dominated by high-fat dairy products processed and red meat [8]. However, discordance in the different MD patterns and consumed food doses had been recognized. Without any doubt, those discrepancies could confine and restrict our knowledge on the health benefit mechanisms of the MD [9]. Due to the above, the medical community along with nutritionists and dieticians take a keen interest in MD and its traits [7]. https://www.academia.edu/45378994/biomedicines_Mediterranean_Diet_as_a_Tool_to_Combat_Inflammation_and_Chronic_Diseases_An_Overview?email_work_card=view-paper food choices can fight inflammation and chronic disease Bottom Line: This is a 2020 paper and since then literally hundreds of papers on the MD have emerged showing how the food plan lowers inflammation and the risk for developing multiple chronic illnesses. Even still, lots of research needs to be done to elucidate the many mechanisms of how food impacts our system and how to optimally individualize dietary recommendations. At this point, our best strategy to prevent and/or recover from any chronic condition is to eat as clean and natural as possible. It has become rather obvious that the further away from a natural diet we get, the sicker we become. On top of that, I have yet to see a full recovery from any health issue without the foundation of a predominantly plant-based, unprocessed, whole foods approach…which is why I keep posting about this subject. All the best to you and yours!
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