Digestive Health Series Part 5: Stress and SIBO

Richmondchironeu • July 22, 2019

Hello again:

Here we go on the last bit before we get into how to recover from these issues.

Low acid can also play a significant role in the development of SIBO and or SIFO , or Small Intestinal Bacterial and/or Fungal Overgrowth, a very annoying problem where the normal gut bugs that are supposed to only inhabit the large intestine, begin to be active in the small intestine…lots of bloating, gas, discomfort, distention and a general increase in toxicity burdens.

This is often related to stress being high for long periods of time, and even concussions, which cause a down-regulation of the vagus nerve. The vagus nerve is the 1oth cranial nerve, which starts inside the skull in the bottom of the brain stem, and travels to the entire chest and gut. It is the opposite of fight and flight and is called the rest and digest nerve because it calms us down and regulates digestion. High stress can result in low vagus function, thus less stomach acid and other digestive enzymes, altered gut motility and more inflammation and food reactions.

High stress also causes increased cortisol production which over time tends to create elevations of histamine in the gut and systemically. This happens because chronically elevated cortisol will cause cell death of the immune cells that normally kill infections, which allows the expansion of the immune cells that make histamine. Histamine elevations can cause nausea, hyper acid production, reflux, headaches, constipation, diarrhea, brain fog and more. You might suspect high histamine causing high acid if you have known seasonal allergies and/or food reactivities and allergies, a history of hives, asthma, and especially if you try the stomach acid supplement trial and it does not help or makes things worse. If that happens, you should either speak with me or an allergist about how to lower histamine and what lab tests might be helpful.

The vagus nerve also controls the junction of the small and large intestine, and under stress, this junction may not work correctly and remain open too long. This results in undigested and rotting food full of large intestine bacteria/yeast coming back into the small intestine where the bacteria and fungus/yeast do not belong, and we get overgrowth of these guys where we do not want them because the vast majority of our gut bacteria belong in the large intestine, not the small. This results in really bad bloating, gas and discomfort, and perhaps constipation with periods of loose stools or vice versa, almost no matter what we eat.

A word on GERD: Gastro-esophageal reflux disorder is when the lower esophageal sphincter remains open and allows stomach contents to rise up into the esophagus…and this hurts and burns. Since the vagus nerve also controls the LES (lower esophageal sphincter), if the vagus nerve tone is low, then this contributes to reflux. Also, too little acid can relax the LES also as can certain foods. Chronic inflammation of the esophagus is a serious condition that may need both medical and natural care together, however, start with the remedies we will go over in the next and final newsletter and if things don’t clear up, see your gastroenterologist for a further work-up, especially if you have any trouble swallowing.

Bottom Line: In the next and last newsletter on this subject, we will go over the steps you can try at home to alleviate all of these issues that we covered in Part 1 through 5, and these issues involve more than stomach acid supplements. See you next week!

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Hello everyone: I think I have mentioned inflammaging before but never really focused on it. So, let’s dig into this interesting topic. Inflammaging is when chronic, low-grade inflammation develops with age as dietary and environmental stress accumulates, contributing to the development of all of the various age-related diseases and health issues. It results from a loss of control over systemic inflammation, which tends to come from an unbalanced and dysregulated immune system. One of the key drivers of inflammaging is diet…which means that one of the key tools to slow and reduce aging is our what we eat as well as what we don’t eat. In this paper, the authors reveal that the typical Western Diet (what science calls the Standard American Diet or S.A.D.) is the best example of a pro-inflammatory diet pattern. “ Conclusion: Inflammation is a key physiological process in immunity and tissue repair. However, during aging it becomes increasingly more chronic. In addition, we found that certain foods such as saturated fats have pro-inflammatory activity. Taking this into account, in this review we have proposed some dietary guidelines as well as a list of compounds present in foods with anti-inflammatory activity. It must be taken into account that the amounts used in the studies that detect anti-inflammatory activity of these compounds are very high, and the intake of a single food to achieve its anti-inflammatory power is not feasible. (My Comment: what this means is that it is the overall dietary pattern that matters the most.) However, the combination of foods rich in compounds with anti-inflammatory activity could exert beneficial effects during aging and in pathologies associated with inflammation and in reducing the detrimental effects of foods with pro-inflammatory activity. Therefore, we can conclude that the compounds in our diet with anti-inflammatory activity could help alleviate the inflammatory processes derived from diseases and unhealthy diets and thereby promote healthy aging. Thus, we can use diet not only for nourishment, but also as medicine.” https://pmc.ncbi.nlm.nih.gov/articles/PMC8389628/ anti-inflammatory diet and health aging https://www.healthline.com/health/5-minute-guide-to-inflamm-aging Bottom Line: We all must age, and how we do so is largely under our own control. To create an anti-inflammatory lifestyle is not that difficult, especially if you put it all together in stages. Start with a clean, whole-food, unprocessed plant-based food plan. And to begin, first focus on what you can add into your menus and use those additions to sort of crowd out the things that are more inflammatory…sugar, refined grains, processed and pre-packaged things. Set realistic goals such as going plant based one or two days a week, or even one meal…just start and gradually work up. It has to be doable so don’t stress. Next, start moving and doing regular exercise at least three times a week…and find what you enjoy doing and focus on that. Then add activities that de-stress you, whether that is socializing, church, meditation, prayer, yoga, etc. Overall, shift your attention to giving love to things that love you back. Sugar, drive-thru and processed food like thingies do not love you back but apples or kiwis or berries or veggies do. Sitting around does not love you back but going for a short walk after a meal does love you back. Hang out and give love to the people you really like to be with, they will most always love you back. Create a love you back lifestyle and see how you feel.
By Mark Smith August 18, 2025
Hello everyone: I frequently hear about mental health issues with the people in our practice. They could be experiencing depression, or anxiety, feel flat, can’t focus or sustain attention, or may not feel well in general. These comments can come from anyone of any age…I can hear from parents about their kids, or it may be themselves experiencing these feeling. So, when I read this paper, it felt important to share it because we all seem to have mobile phones. Here is how the paper is summarized: “Concern about how smartphones affect users is widespread: half of American smartphone users—and 80% of those under age 30—worry that they use their device too much, and correlational research suggests that smartphone use is negatively related to mental health and cognitive functioning. However, few large-scale experiments have tested for causal effects. We report such an experiment, finding that blocking mobile internet for 2 weeks reduces smartphone use and improves subjective well-being (SWB) (including life satisfaction and positive affect), mental health (more than antidepressants), and sustained attention (as much as being 10 years younger). Despite the many benefits mobile internet offers, reducing the constant connection to the digital world can have large positive effects.” https://academic.oup.com/pnasnexus/article/4/2/pgaf017/8016017?utm_source=klaviyo&utm_medium=email&utm_campaign=%28Email%20-%20Chris%20Kresser%20General%20News%29%20Chris%27s%20Friday%20Favorites&utm_term=randomized%20controlled%20trial&utm_content=randomized%20controlled%20trial&_kx=fARhTo_gi8X3B_2-MaeO_RyzUl9tvT3tr4re-Dy7cNQ.my75y6 Bottom Line: It seems like a smartphone ‘timeout’ can be very beneficial for mental, emotional, physical health and can be an important part of stress reduction. The world today, with nearly instant communications, the almost constant bad and anxiety promoting news, and the fast pace of data consumption can add up to significantly stress us out and pull us down…or just simple keep us distracted. From what I can see, a ‘timeout’ may be just what the doctor ordered.
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