Can Diet Lower Inflammation Markers?

Mark Smith • October 29, 2025

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Health News Update: Can Diet Lower Inflammation Markers?                  10.27.25

Hello everyone: You have probably heard me say, over and over, how inflammation will cause, perpetuate, and/or aggravate every known human ailment, even aging and recovery processes. Also, most everyone has heard of the anti-inflammatory diet or food plan and the most well-known is the Mediterranean Diet (MD). And conversely, most of our country consumes the most pro-inflammatory diet known, the Standard American Diet, or the S.A.D. Here is some news to help understand why moving to a plant-centric food plan can save your life:

 

“Although inflammation is a normal defense mechanism that protects the body against infection or other insults, pathological inflammation is associated with tissue damage and disease. In this sense, low-grade systemic inflammation appears to play an important role in the

pathophysiology of obesity, insulin resistance, CVD (Cardio-Vascular Disease) and the anomalous coagulation process. The chronic inflammatory response is characterized by abnormal cytokine production and the activations of inflammatory signaling pathways.

 

A growing body of evidence suggests that the protective effects of the MD may result, at least in part, from its anti-inflammatory properties. Low-grade chronic inflammation has been involved as a potential mediator for the development of many cardio-metabolic diseases. Therefore, studying the relation between the diet quality and inflammatory markers will be interesting.

 

Changes in the traditional MDP (Mediterranean Dietary Pattern) toward the modern Western diet are taking place, representing a dietary globalization. Nowadays, a diet rich in meat, processed foods and sweets is increasingly more common in the population, affecting young and adult subjects. However, a high adherence to the MDP is related to a lower risk of suffering pathologies such as cardiovascular diseases or cancer. In this sense, the beneficial effect of the MDP against CVD has been mainly attributed to its effects controlling classical atherosclerosis risk factors. Lately, it has been suggested that an anti-inflammatory effect in the vascular wall may be another important mechanism to explain the link between the MDP and low cardiovascular mortality. The important role of inflammation in the pathogenesis of atherosclerosis has led to the belief that dietary preventive measures act in part by modifying related inflammatory pathways.”

 

https://www.academia.edu/88885246/Adherence_to_the_Mediterranean_Diet_and_Inflammatory_Markers?email_work_card=view-paper

 

Bottom Line: To a great and significant extent, your diet is your destiny. Shifting to a Green Mediterranean style food plan is not only delicious, but also anti-inflammatory and longevity promoting. In our country, the average healthspan is 10 to 15 years less than the lifespan. To not be average, but exceptional and bump your healthspan up to within a year of your lifespan, and to bump them both way up…go predominantly plant based as soon as you can

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Hello everyone: I think I have mentioned inflammaging before but never really focused on it. So, let’s dig into this interesting topic. Inflammaging is when chronic, low-grade inflammation develops with age as dietary and environmental stress accumulates, contributing to the development of all of the various age-related diseases and health issues. It results from a loss of control over systemic inflammation, which tends to come from an unbalanced and dysregulated immune system. One of the key drivers of inflammaging is diet…which means that one of the key tools to slow and reduce aging is our what we eat as well as what we don’t eat. In this paper, the authors reveal that the typical Western Diet (what science calls the Standard American Diet or S.A.D.) is the best example of a pro-inflammatory diet pattern. “ Conclusion: Inflammation is a key physiological process in immunity and tissue repair. However, during aging it becomes increasingly more chronic. In addition, we found that certain foods such as saturated fats have pro-inflammatory activity. Taking this into account, in this review we have proposed some dietary guidelines as well as a list of compounds present in foods with anti-inflammatory activity. It must be taken into account that the amounts used in the studies that detect anti-inflammatory activity of these compounds are very high, and the intake of a single food to achieve its anti-inflammatory power is not feasible. (My Comment: what this means is that it is the overall dietary pattern that matters the most.) However, the combination of foods rich in compounds with anti-inflammatory activity could exert beneficial effects during aging and in pathologies associated with inflammation and in reducing the detrimental effects of foods with pro-inflammatory activity. Therefore, we can conclude that the compounds in our diet with anti-inflammatory activity could help alleviate the inflammatory processes derived from diseases and unhealthy diets and thereby promote healthy aging. Thus, we can use diet not only for nourishment, but also as medicine.” https://pmc.ncbi.nlm.nih.gov/articles/PMC8389628/ anti-inflammatory diet and health aging https://www.healthline.com/health/5-minute-guide-to-inflamm-aging Bottom Line: We all must age, and how we do so is largely under our own control. To create an anti-inflammatory lifestyle is not that difficult, especially if you put it all together in stages. Start with a clean, whole-food, unprocessed plant-based food plan. And to begin, first focus on what you can add into your menus and use those additions to sort of crowd out the things that are more inflammatory…sugar, refined grains, processed and pre-packaged things. Set realistic goals such as going plant based one or two days a week, or even one meal…just start and gradually work up. It has to be doable so don’t stress. Next, start moving and doing regular exercise at least three times a week…and find what you enjoy doing and focus on that. Then add activities that de-stress you, whether that is socializing, church, meditation, prayer, yoga, etc. Overall, shift your attention to giving love to things that love you back. Sugar, drive-thru and processed food like thingies do not love you back but apples or kiwis or berries or veggies do. Sitting around does not love you back but going for a short walk after a meal does love you back. Hang out and give love to the people you really like to be with, they will most always love you back. Create a love you back lifestyle and see how you feel.
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Hey there everyone: As you know, inflammation causes, perpetuates, and/or aggravates every known human condition, including aging. As we age, we become more vulnerable to non-communicable diseases such as heart attack, stroke, high blood pressure, cancer, diabetes, dementia, arthritis and more. How we eat can massively reduce our inflammatory burden and promote health as we age. It is your choice. One reason that I keep writing on this is that I keep running into the mindset that these diseases are inevitable and that there is nothing we can do about it. Plus, because there are so many different diets for sale out there, it becomes hard to know what to eat. What is important for you to know is that there is a growing scientific consensus about what to eat, but the media rarely mention it and our public health authorities don’t either. It definitely seems like money is more important than our health. So…consuming an overall low-inflammatory diet is what the science is adding up to show it is the healthiest way to go, plus it actually gives you power over your future. This is a great article worth the time it takes to read it as it is pretty comprehensive. Bottom Line: “To adopt an anti-inflammatory dietary pattern, it is recommended to replace refined grains with whole grains, substitute healthy fats (such as nuts, seeds and fatty fish) for saturated and trans fats and increase the consumption of colorful fruits and vegetables while reducing the intake of sugary and processed foods. Additionally, choosing lean protein sources like fish and legumes over red and processed meats, using herbs and spices (such as turmeric, ginger, garlic and cinnamon) in place of excessive salt and sugar and consuming probiotic-rich foods (such as yogurt and kefir) instead of processed and sugary snacks are advised. These dietary adjustments can help mitigate inflammation and promote overall health.” https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/overview-of-antiinflammatory-diets-and-their-promising-effects-on-noncommunicable-diseases/AA3166846841DCC1B219C063F52E2A7F (anti-inflammatory diet)
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