Health News Update: Alcohol and Brain: No Safe Level of Consumption

Mark Smith • November 17, 2025

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Health News Update: Alcohol and Brain: No Safe Level of Consumption                     11.17.25

Hello again everyone: This blog is for those who are interested in preserving maximal brain function, memory, and overall health. Pay special attention if you have any relatives, near or close, that have any type of dementia, or if you have any level of brain fog. These are all neurodegenerative disorders that have inflammation as a component. How this ties in with alcohol consumption is the focus of this new research paper.

 

ABSTRACT

Objectives To investigate the relationship between alcohol consumption and dementia.

WHAT THIS STUDY ADDS

In the largest combined observational and genetic study to date, light alcohol consumption was associated with the lowest dementia risk observationally, but genetic analyses showed a monotonic increasing dementia risk with increased alcohol intake. Mendelian randomization suggests a causal role of alcohol consumption in increasing dementia risk, with no evidence supporting a protective effect at any consumption level.

HOW MIGHT THIS STUDY AFFECT RESEARCH, PRACTICE OR POLICY

These findings challenge the notion that low levels of alcohol are neuroprotective and suggest that public health efforts to reduce alcohol use disorder could significantly lower dementia incidence. Halving the population prevalence of alcohol use disorder may reduce dementia cases by up to 16%, highlighting alcohol reduction as a potential strategy in dementia prevention policies.

 

https://ebm.bmj.com/content/ebmed/early/2025/09/16/bmjebm-2025-113913.full.pdf

 

Bottom Line: This paper clarifies earlier observations that light to moderate alcohol consumption had some benefit by showing that no level of alcohol consumption is safe for the brain. Use this information to shape your alcohol consumption as it relates to your health values, your genetic risks, your current health, and other individual factors. No alcohol is the best practice. To me, at this point in my life, alcohol consumption is like throwing a heavy blanket over the light of my soul…there is just no benefit, so I avoid it completely. What are your thoughts?

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Health News Update: Sleep Timing, Mood & Performance 4.6.26 Hello everyone: In taking a history at the start of a healthcare process, I often find people of all ages have sleep schedules that do not match optimal circadian rhythms and have un-knowingly contributed to degrading their health. Sleep is a significant component of leading an anti-inflammatory lifestyle as it fosters autophagy (an immune based essential self-cleaning function, hormonal regulation, stress reduction, immune resilience, optimal aging, and more. As it turns out, getting your sleep timing right lowers depression, reduces morning fatigue, improves physical functions, and can markedly increase your ability to think, recall things and overall cognitive functions. Proper sleep timing aligned with our natural circadian clocks may also decrease mortality risks. Background There is conflict between living according to our endogenous biological rhythms and our external environment, with disruptions resulting in negative consequences to health and performance. This is often documented in shift work and jet lag , but ‘societal norms’ (eg, typical working hours) can create profound issues for ‘night owls’, people whose internal biological timing predisposes them to follow an unusually late sleep-wake cycle. Night owls have also been associated with health issues, mood disturbances, poorer performance and increased mortality rates . Results Overall, participants demonstrated a significant advance of ∼2 h in sleep/wake timings as measured by actigraphy and circadian phase markers (dim light melatonin onset and peak time of the cortisol awakening response), whilst having no adverse effect on sleep duration. Notably, the phase advance was accompanied by significant improvements to self-reported depression and stress, as well as improved cognitive (reaction time) and physical (grip strength) performance measures during the typical ‘suboptimal’ morning hours. https://www.sciencedirect.com/science/article/abs/pii/S1389945719301388?via%3Dihub resetting sleep timing improves brain function and overall health. Bottom Line: For long term health, assisting recovery, optimal aging, improving immune resilience, lowering your total inflammatory burden thus reducing your risk for developing chronic diseases…it looks like a very good idea to get your sleep cycles in line with your natural biological rhythms. The researchers aimed to accomplish this using only simple practical natural lifestyle methods…no medications. Here is some of what they did: · Avoid blue light after dark. · Get some early morning sunshine…even 5 minutes will help. · Exercise in the morning or early afternoon. · Adopt early time restricted feeding schedules (eTRF). · Fix a time to sleep and stick to it. If you have any chronic health issues, or just want to optimize the aging process, simply adopt a few simple lifestyle strategies. I have seen this clinically be one of the major keys to the success when it comes to overcoming fatigue, brain fog, digestive issues, and any chronic health problem. Best wishes to you for a healthy life!
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Health News Update: How To Fight Inflammation and Chronic Disease 3.23.26 Hello again everyone: You might wonder why I keep focusing on food…so here are some of the reasons: food choices are the leading cause of death in the U.S. and spreading around the world. Poor food choices lead to inflammation which slowly destroy health. It is that simple, plain, and clear and backed by research. The next question: how do we fight back? Introduction The positive impact of food on health was postulated by the ancient Hippocrates, father of modern medicine with his famous quote: “Let food be thy medicine and medicine be thy food” [1]. In the 21st century, scientists have focused on the effect of nutritional habits in diseases. Nowadays, it is well documented that food plays a noteworthy role in the pathogenesis of chronic diseases namely cardiovascular diseases (CVD), metabolic syndrome, diabetes mellitus type II, and cancer [2–5], as it correlates with others with the lipid pattern, the blood pressure, and the endothelial function. The scientists examine the effect of nutritional habits on disease emergence and progression in both individual nutrient intake and dietary patterns models. Worldwide, two dietary patterns are usually compared—the Mediterranean diet (MD) and the Western diet (WD) [3,6]. The Mediterranean diet reflects the food culture of most Mediterranean countries based on olive oil consumption, seasonal fresh vegetables, cereals, and plants in balance with low consumption of meat [7]. The Western diet, on the contrary, is dominated by high-fat dairy products processed and red meat [8]. However, discordance in the different MD patterns and consumed food doses had been recognized. Without any doubt, those discrepancies could confine and restrict our knowledge on the health benefit mechanisms of the MD [9]. Due to the above, the medical community along with nutritionists and dieticians take a keen interest in MD and its traits [7]. https://www.academia.edu/45378994/biomedicines_Mediterranean_Diet_as_a_Tool_to_Combat_Inflammation_and_Chronic_Diseases_An_Overview?email_work_card=view-paper food choices can fight inflammation and chronic disease Bottom Line: This is a 2020 paper and since then literally hundreds of papers on the MD have emerged showing how the food plan lowers inflammation and the risk for developing multiple chronic illnesses. Even still, lots of research needs to be done to elucidate the many mechanisms of how food impacts our system and how to optimally individualize dietary recommendations. At this point, our best strategy to prevent and/or recover from any chronic condition is to eat as clean and natural as possible. It has become rather obvious that the further away from a natural diet we get, the sicker we become. On top of that, I have yet to see a full recovery from any health issue without the foundation of a predominantly plant-based, unprocessed, whole foods approach…which is why I keep posting about this subject. All the best to you and yours!
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