Health New Update: Food, Inflammation, & Chronic Diseases

Mark Smith • November 10, 2025

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Health New Update: Food, Inflammation, & Chronic Diseases                                  11.10.25

Hello everyone: The research and science continue to reinforce the connection between inflammation and virtually all chronic health conditions, from heart attack, to cancer, to dementia, to everyday fatigue, depression, anxiety, insomnia, as well as aches and pains.

 

“Inflammation is now widely believed to be a cause of atherosclerosis [1,2]. Moreover, inflammation is an underlying pathophysiological mechanism in many other chronic diseases, including obesity [3] and type 2 diabetes mellitus [4], in addition to cardiovascular disease (CVD) [5]. Multiple factors contribute to this inflammatory process, including age, sex, physical activity, smoking, the use of certain medications, and diet [6]. Therefore, lifestyle and diet have a significant impact on health which is based, at least in part, on its association with inflammation [7,8].

 

Diet is a major determinant of inflammation, and a number of markers can be used to assess the inflammation in human nutrition studies [9,10]. Pro-inflammatory biomarkers, such as tumor necrosis factor-α (TNF-α), C-reactive protein (CRP), or cell adhesion molecules have been used as indices of the effect of dietary patterns on low-grade inflammatory status [11–15]. In fact, the inverse association of a Mediterranean-style diet with major chronic disease is partially attributed to the anti-inflammatory properties of some of their foods such as fruits, extra-virgin olive oil, red wine, or nuts [16,17], and some of their bioactive components, such as polyphenols [18]. In contrast, certain components of diet, such as red meat and processed foods, are considered to be pro-inflammatory stimulants [19,20].”

 

https://www.academia.edu/48088815/The_Role_of_Dietary_Inflammatory_Index_in_Cardiovascular_Disease_Metabolic_Syndrome_and_Mortality?email_work_card=view-paper

 

Bottom Line: Just looking at the diet advice that is offered on all types of media can leave most of us feeling confused and frustrated. However, there is a growing scientific consensus of what makes a healthy diet, but you won’t find this information easily…there are just too many financial interests that would be negatively impacted if we all ate properly.

 

Imagine lowering your cancer risk by 25% (which means 80,000 cancer cases in the U.S. per year are diet related), or lowering your risk of cardiovascular disease by 90%, and doing this just by consuming a delicious unprocessed, whole-food, predominantly plant-based food plan. This food plan is called the Green Mediterranean diet and is easy to adopt.

 

If you are not a good chef, becoming one can save your life…plus it can be a fun, relaxing, enjoyable and social activity that not only saves money but supports your health and wellbeing. Invest in some cookbooks and watch your health savings account grow to create a safer future.

 

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Hello everyone: I think I have mentioned inflammaging before but never really focused on it. So, let’s dig into this interesting topic. Inflammaging is when chronic, low-grade inflammation develops with age as dietary and environmental stress accumulates, contributing to the development of all of the various age-related diseases and health issues. It results from a loss of control over systemic inflammation, which tends to come from an unbalanced and dysregulated immune system. One of the key drivers of inflammaging is diet…which means that one of the key tools to slow and reduce aging is our what we eat as well as what we don’t eat. In this paper, the authors reveal that the typical Western Diet (what science calls the Standard American Diet or S.A.D.) is the best example of a pro-inflammatory diet pattern. “ Conclusion: Inflammation is a key physiological process in immunity and tissue repair. However, during aging it becomes increasingly more chronic. In addition, we found that certain foods such as saturated fats have pro-inflammatory activity. Taking this into account, in this review we have proposed some dietary guidelines as well as a list of compounds present in foods with anti-inflammatory activity. It must be taken into account that the amounts used in the studies that detect anti-inflammatory activity of these compounds are very high, and the intake of a single food to achieve its anti-inflammatory power is not feasible. (My Comment: what this means is that it is the overall dietary pattern that matters the most.) However, the combination of foods rich in compounds with anti-inflammatory activity could exert beneficial effects during aging and in pathologies associated with inflammation and in reducing the detrimental effects of foods with pro-inflammatory activity. Therefore, we can conclude that the compounds in our diet with anti-inflammatory activity could help alleviate the inflammatory processes derived from diseases and unhealthy diets and thereby promote healthy aging. Thus, we can use diet not only for nourishment, but also as medicine.” https://pmc.ncbi.nlm.nih.gov/articles/PMC8389628/ anti-inflammatory diet and health aging https://www.healthline.com/health/5-minute-guide-to-inflamm-aging Bottom Line: We all must age, and how we do so is largely under our own control. To create an anti-inflammatory lifestyle is not that difficult, especially if you put it all together in stages. Start with a clean, whole-food, unprocessed plant-based food plan. And to begin, first focus on what you can add into your menus and use those additions to sort of crowd out the things that are more inflammatory…sugar, refined grains, processed and pre-packaged things. Set realistic goals such as going plant based one or two days a week, or even one meal…just start and gradually work up. It has to be doable so don’t stress. Next, start moving and doing regular exercise at least three times a week…and find what you enjoy doing and focus on that. Then add activities that de-stress you, whether that is socializing, church, meditation, prayer, yoga, etc. Overall, shift your attention to giving love to things that love you back. Sugar, drive-thru and processed food like thingies do not love you back but apples or kiwis or berries or veggies do. Sitting around does not love you back but going for a short walk after a meal does love you back. Hang out and give love to the people you really like to be with, they will most always love you back. Create a love you back lifestyle and see how you feel.
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