Covid-19 & Health Update: US Dietary Patterns Impair Immune Function

RVAchironeuro • August 12, 2021

Hello once again everyone:

We all know that alongside the pandemic of Covid-19, there is a pandemic of chronic disease that creates comorbidities, and it is this combination that is killing our country and other parts of the world. Here is a paper that outlines how the Standard American Diet (SAD) contributes to alterations in immune competence through changes in our gut immune system and gut microbiome. Here are some quotes from the two links below that are both about the same study:

“Eating a Western diet impairs the immune system in the gut in ways that could increase risk of infection and inflammatory bowel disease, according to a study from researchers at Washington University School of Medicine in St. Louis and Cleveland Clinic.

  The study, in mice and people, showed that a diet high in sugar and fat causes damage to Paneth cells, immune cells in the gut that help keep inflammation in check. When Paneth cells aren’t functioning properly, the gut immune system is excessively prone to inflammation, putting people at risk of inflammatory bowel disease and undermining effective control of disease-causing microbes.”

  “Our findings provide a mechanistic link between poor diet and inhibition of gut innate immunity and uncover an effect of FXR activation in gut inflammation.”

Bottom Line:

This was a short-term study that revealed the SAD of high fat, high sugar combination derails gut health through multiple complex mechanisms. What they do not note is that gut inflammation will permeate our entire body and thus impair health in other organs and functions, especially brain. For you and me, this simply means that consumption a diet rich in organic, unprocessed whole foods lower in animal-based products and high in plant-based foods can reasonably be expected to improve health by lowering our inflammatory burden…as long as we have not gone beyond the point of no return. The only way to know is to actually eat right and see what happens. In this scenario, most have much to gain and possibly much to lose as well.

One of the better plans and the best description of this approach, so far, has been through the book “The Longevity Diet” by Valter Longo, PhD. Additionally, this book has a great science-based approach. Why is that important? Because most of us are not aware that there is a growing consensus of what constitutes a healthy food plan. Why are we not aware of this? Because when we look at the internet or other sources, there are at least several hundred diet books and plans and recommendations which make it look like no-one knows what the heck they are talking about. When you sort through all the hype, the dietary approach that Dr. Longo puts forth is the one with the most science and common sense. However, the science is never settled, and new information is always being found about food and health. Right now, we do know that the SAD is not good for us, so any upgrade would be helpful!!

By Mark Smith March 2, 2026
New Title
By Mark Smith February 23, 2026
New Title
By Mark Smith February 16, 2026
New Title
By Mark Smith February 2, 2026
New Title
By Mark Smith January 26, 2026
New Title
By Mark Smith January 19, 2026
New Title
By Mark Smith January 12, 2026
New Title
By Mark Smith January 5, 2026
Health News Update: Happy New Year 2026! 1.5.26 Hey there everyone: Here is some news you can use to help you age optimally. I have written before about circadian rhythms and meal timing where it has been shown that eTRF (early time restricted feeding) has many benefits. But what happens as we age and shift our mealtimes away from our natural circadian clocks? Here are some snippets from this paper: “Chrononutrition, the study of the timing of eating, has emerged as a modifiable risk factor for adverse health outcomes The role of eating schedules is biologically relevant as dietary intake acts as an environmental cue influencing the circadian clocks of peripheral metabolic tissues and therefore can contribute to circadian misalignment and internal desynchrony 2 , 10 . The emerging evidence largely suggests that later mealtimes, particularly eating during the biological evening, is detrimental to health, Physical and psychological illnesses, including fatigue, oral health problems, depression, anxiety, and multimorbidity, are primarily associated with later breakfast. Later breakfast timing is also associated with increased mortality Importantly, eating breakfast later with aging was linked to a higher risk of death” https://www.nature.com/articles/s43856-025-01035-x meal timing important for health Bottom Line: While this paper focuses on the elderly, it is certainly applicable to all of us. I have seen significant health benefits when people adopt eTRF patters…from better digestion to weight loss, to better sleep, to more energy! Here are two links to my earlier blogs for the info on when to eat for optimal health: https://www.richmondchironeuro.com/health-news-update-when-you-eat-is-critical-to-long-term-health https://www.richmondchironeuro.com/health-news-update-when-we-eat-is-as-critical-as-what-we-eat
By Mark Smith December 29, 2025
Health News Update: Health is Your Most Valuable Asset 12.29.2025 Hello again everyone: This blog is a follow up to last week’s Christmas wishes, because it is my sincere wish for each of you that you fully embrace a healthy lifestyle for 2026 and beyond. Health is built on many components, and if you were to choose just one to get started, it would be to seriously upgrade your food choices, which specifically means a whole food, unprocessed or minimally processed (home cooking), plant-based food plan. Why? As you have heard me say, over and over, that inflammation will cause, perpetuate, and/or aggravate ALL chronic conditions and diseases plus it makes us susceptible to acute illness such as infections (flu, mono, Covid, etc.). As noted in the Journal of the American Medical Association (1), the Standard American Diet (SAD) is the leading cause of death and disability in our country and many others. It used to be that the leading causes of death were Communicable Diseases, i.e., infections. Today, the leading causes of death are Non-Communicable Diseases (NCD’s) such as heart disease, cancer, high blood pressure, stroke, diabetes, dementia…these chronic degenerative diseases are responsible for over 70% of all deaths worldwide. (2) Additionally, while we are living longer, we are living sicker. This means that our healthspan is about 10 to 15 years shorter than our lifespan…this is a deplorable condition that I have seen so many suffer through with progressive disability, suffering, and an early and unpleasant death spiral. At this moment, about 40% of us have multiple chronic health conditions while nearly 60% are burdened with at least one chronic health diagnosis…and this situation has only been forecasted to worsen significantly. (3,4) The tragedy is that this situation is largely preventable. You already know that food is the leading cause of death and disability…so what foods are they talking about? The researchers are talking about the Standard American Diet, also known as SAD…which is unfortunately a very fitting abbreviation. The SAD is notable for a high consumption of processed and ultra-processed foods, added sugars, saturated fats, refined carbohydrates, processed meats, red meat, additives, colorings, flavor enhancers, sugary drinks, higher pesticide and chemical burdens, and refined grains…and lacking in clean sources of vegetables, fruits, whole grains, nuts, seeds, legumes, and leaner protein sources. (5) The SAD diet is notable for high energy density and low nutrient density...a recipe for illness. All cellular processed require nutrition, not just calories. No single food has all of the nutrients, vitamins, minerals, phytonutrients, fiber, protein, fat, and carbohydrates that we need to thrive and remain robust and resilient. Consuming a diet that results in insufficiency, deficiency, or an excess of nutrients will eventually lead to some type of illness, disease, or condition as well as predispose you to becoming chronically inflamed, ill, or just sick. The SAD diet has been linked to many chronic diseases primarily because it leads to uncontrolled, chronic, background inflammation that drives health degeneration. Current research states that on average both children and adults consume 60% of their daily caloric intake from ultra-processed foods and only 10% of us meet the daily requirements for recommended fruit and vegetable intake (5, 6, 7) and 73% of our food supply is ultra-processed. Additionally, many studies have revealed that this type of ‘food’ is directly linked to many diseases and conditions and has been categorized as a high inflammatory potential diet. (8) An inflammatory dietary pattern will cause, perpetuate, and/or aggravate all of the leading causes of death and disability…or as some research puts it, “The chronic inflammatory state significantly contributes to the development and progression of many noncommunicable disease processes, including cancer, cardiovascular disease, and neurocognitive decline.” (13) On the flip side, a diet that consists of minimally processed, whole food, plant-based sources of nutrient dense, low inflammatory potential, and calorically appropriate foods is associated with fewer diseases, better health, less disability and an overall higher quality of life. It even helps when you are already not feeling well. (9,10,11,12,13,14) In my practice and clinical experience, without an optimal food plan, no amount of adjustments, vitamins, herbs, exercise, or stress reduction will work nearly as well as they should, if at all. Additionally, you should know that if you would like to experience healthy aging, an anti-inflammatory food upgrade is essential…and this includes both physically and cognitively. By now, I hope you are at least curious about consuming an anti-inflammatory, unprocessed, clean, whole food plant-based dietary lifestyle. This is not a sprint…we are all in it for the long haul and slow and steady (consistency) wins the race. Invest in yourself by taking classes in how to create your optimal food plan. I have recently taken several courses and gotten a lot out of them and upgraded our foods even more. (15,16,17,18,19) Undoubtably there are more classes out there…let me know what you find! Remember, you can start slowly and gradually work your way into this upgrade/shift. For example, in week one, you can start with 2 or 3 plant based lunches and next week add a breakfast, and so on. You can reduce your animal foods gradually at a pace you can be comfortable with. Just start…go plant-based and see what happens…you have nothing to lose (except some unwanted pounds and inflammation) and everything to gain. Part of being a good steward and tending your Temple is realizing that food is an essential part of our worship. We would never put diesel into our gas tank, nor should we put ultra-processed ‘food like things’ into our Temple. Now that you know this, what will you choose to do? So, this is my New Years wish for you and yours: freedom from disability, illness, and disease, a massive recovery if you need it, and the feeling of vibrant health always. Thank you for your time and attention…all the best for 2026! References: 1. https://jamanetwork.com/journals/jama/fullarticle/2678018 (see Figure 2) 2. https://pmc.ncbi.nlm.nih.gov/articles/PMC10830426/ 3. https://chronicdisease.org/wp-content/uploads/2022/04/FS_ChronicDiseaseCommentary2022FINAL.pdf 4. https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2022.1082183/full 5. https://www.medicalnewstoday.com/articles/western-diet 6. https://foodtank.com/news/2022/11/database-indicates-u-s-food-supply-is-73-percent-ultra-processed/ 7. https://www.medicalnewstoday.com/articles/overall-diet-quality-may-be-more-important-than-how-much-ultra-processed-foods-you-eat#Why-ultra-processed-foods-are-unhealthy 8. https://www.medicalnewstoday.com/articles/overall-diet-quality-may-be-more-important-than-how-much-ultra-processed-foods-you-eat#How-to-have-a-more-healthy-diet 9. https://health.unl.edu/health-benefits-anti-inflammatory-diet-10-foods-eat-and-6-avoid/ 10. https://www.hopkinsmedicine.org/health/wellness-and-prevention/anti-inflammatory-diet 11. https://www.henryford.com/blog/2020/07/health-benefits-antiinflammatory-diet 12. https://www.health.harvard.edu/staying-healthy/quick-start-guide-to-an-antiinflammation-diet 13. https://www.ncbi.nlm.nih.gov/books/NBK597377/ 14. https://pmc.ncbi.nlm.nih.gov/articles/PMC8389628/ 15. https://simplyplantbasedkitchen.com/ 16. https://thriving.foodrevolution.org/join/?frn_source=blog&frn_medium=link&frn_campaign=ppt&frn_content=menu 17. https://hellonutritarian.com/nutritarian-power-prep-program/ 18. https://cookingcourse.forksoverknives.com/ 19. https://www.drfuhrman.com/blog/210/beginners-guide
More Posts