Health Update: Pro-inflammatory Diet May Worsen Arthritis and Pain

Mark Smith • April 29, 2024

Hello everyone:

 

As science progresses, we are learning a lot about how our bodies work. As you know, it is my mantra that inflammation causes, perpetuates, and/or aggravates every known human condition, including how well and how fast or slow we age (yes, I am talking to YOU!). Here is an interesting study about knee arthritis and how an inflammatory diet can be associated with increased pain and a more severe joint destructive trajectory over your lifetime:


“Conclusion: A proinflammatory diet, as indicated by a higher DII score, may be associated with a greater pain score and higher risk of more severe pain trajectory over 10 years. However, inconsistent findings related to structural changes suggest a discordance between the potential impact of diet on structural damage and pain in knee OA.”


https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/acr.25307


Bottom Line:

 

Consuming a lower or anti-inflammatory diet can have a positive impact on your healthspan, lifespan, aging profile, as well as how fast or slow our joints degenerate. In their paper, they state “that inflammation has emerged as an important factor in the progression and pathology of knee osteoarthritis.”

 

Additionally, they state that: The DII scores were developed using peer-reviewed articles by assigning a score to each food component that has been found to have robust evidence for its ability to influence systemic inflammation.1112 Numerous studies have explored the connections between DII scores and various diseases, revealing that higher scores are linked to increased risks of cardiovascular disease,13 cancer,14 and osteoporosis and fracture.12 High DII scores, associated with higher intakes of food groups including fats, oils, sweets and sodas, meat, fish, poultry, beans and eggs, and lower intakes of whole grains, fruits, and vegetables, are associated with a greater prevalence of radiographic symptomatic KOA and knee pain.1516Previous meta-analyses have indicated that high DII components, such as processed meat and sugar, were associated with an increased risk of cardiovascular disease, and higher consumption of red and processed meat, high-salt foods, and alcoholic drinks has been linked to a greater risk of colorectal and stomach cancer.1718

 

If you want to be as healthy as possible, have the best life possible, feel and look your best, then it may be a really great idea to eat a low inflammatory diet. Friends don’t let friends eat that ‘stuff’. Now that you know, what will you do? How will you use this information to guide your lifestyle choices? 

By Mark Smith March 23, 2026
Health News Update: How To Fight Inflammation and Chronic Disease 3.23.26 Hello again everyone: You might wonder why I keep focusing on food…so here are some of the reasons: food choices are the leading cause of death in the U.S. and spreading around the world. Poor food choices lead to inflammation which slowly destroy health. It is that simple, plain, and clear and backed by research. The next question: how do we fight back? Introduction The positive impact of food on health was postulated by the ancient Hippocrates, father of modern medicine with his famous quote: “Let food be thy medicine and medicine be thy food” [1]. In the 21st century, scientists have focused on the effect of nutritional habits in diseases. Nowadays, it is well documented that food plays a noteworthy role in the pathogenesis of chronic diseases namely cardiovascular diseases (CVD), metabolic syndrome, diabetes mellitus type II, and cancer [2–5], as it correlates with others with the lipid pattern, the blood pressure, and the endothelial function. The scientists examine the effect of nutritional habits on disease emergence and progression in both individual nutrient intake and dietary patterns models. Worldwide, two dietary patterns are usually compared—the Mediterranean diet (MD) and the Western diet (WD) [3,6]. The Mediterranean diet reflects the food culture of most Mediterranean countries based on olive oil consumption, seasonal fresh vegetables, cereals, and plants in balance with low consumption of meat [7]. The Western diet, on the contrary, is dominated by high-fat dairy products processed and red meat [8]. However, discordance in the different MD patterns and consumed food doses had been recognized. Without any doubt, those discrepancies could confine and restrict our knowledge on the health benefit mechanisms of the MD [9]. Due to the above, the medical community along with nutritionists and dieticians take a keen interest in MD and its traits [7]. https://www.academia.edu/45378994/biomedicines_Mediterranean_Diet_as_a_Tool_to_Combat_Inflammation_and_Chronic_Diseases_An_Overview?email_work_card=view-paper food choices can fight inflammation and chronic disease Bottom Line: This is a 2020 paper and since then literally hundreds of papers on the MD have emerged showing how the food plan lowers inflammation and the risk for developing multiple chronic illnesses. Even still, lots of research needs to be done to elucidate the many mechanisms of how food impacts our system and how to optimally individualize dietary recommendations. At this point, our best strategy to prevent and/or recover from any chronic condition is to eat as clean and natural as possible. It has become rather obvious that the further away from a natural diet we get, the sicker we become. On top of that, I have yet to see a full recovery from any health issue without the foundation of a predominantly plant-based, unprocessed, whole foods approach…which is why I keep posting about this subject. All the best to you and yours!
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