Health Update: Anti-Inflammatory Drugs May Prolong Pain

RVAchironeuro • May 26, 2022

Hello everyone:

Here is some news that has been known for quite some time and is now making headlines once again. The following quote sums it up quite nicely:

“A new study questions the conventional wisdom of using steroids and anti-inflammatory drugs like  ibuprofen   to treat low  back pain   if exercise and other non-drug therapies don’t work right away.

Those medications offer relief from acute pain but may actually increase a person’s chances of developing chronic pain, said the study published in  Science Translational Medicine . The study indicates that inflammation is a normal part of recovering from a painful injury and that inhibiting inflammation may result in more-difficult-to-treat chronic pain.”

And from the article referenced from the above link:

“Together, our results suggest that active immune processes confer adaptation at the acute pain stage, and impairment of such inflammatory responses in subjects with acute LBP (or TMD) increases the risk of developing chronic pain. These adaptive inflammatory responses are intrinsically transcriptionally driven, probably modified by both genetics and environmental factors, and can be inhibited by steroids and NSAIDs. These responses are transient, which is probably the main reason why they were previously overlooked. Our conclusions may have a substantial impact on medical treatment of the most common presenting complaints to health care professionals. Specifically, our data suggest that the long-term effects of anti-inflammatory drugs should be further investigated in the treatment of acute LBP and likely other pain conditions.”

Bottom Line:

If you have an acute injury, there is research literature stating that the use of anti-inflammatory medications of any type should not be used for more than 5 days if at all possible. This is because the medication will delay or abort the resolution process of inflammation and set the stage for chronic inflammation and pain as well as delayed or poor or ineffective healing. (See the link at the bottom of the page, and if interested go to page 8 and 9.) Alternatives that do not interfere with healing and resolution are such things as: chiropractic adjustments; physical therapy; Curcumin from Turmeric; Boswellia: Ginger; Omega-3 Essential Fatty Acids. (These supplements should not be used if you are on blood thinning medications). There are many more pro-resolution and anti-inflammatory resources for chronic conditions, however, here we are referencing mainly acute issues. Talk with the prescribing physician about this issue if you are on longer term anti-inflammatory medications about any possible alternatives. You can also reach out to us as this is a special interest of ours because if you have read our blog before, then you know that inflammation causes, perpetuates, and/or aggravates every known human ailment and that we have natural strategies to help protect your health from inflammation.

 

 

By Mark Smith March 23, 2026
Health News Update: How To Fight Inflammation and Chronic Disease 3.23.26 Hello again everyone: You might wonder why I keep focusing on food…so here are some of the reasons: food choices are the leading cause of death in the U.S. and spreading around the world. Poor food choices lead to inflammation which slowly destroy health. It is that simple, plain, and clear and backed by research. The next question: how do we fight back? Introduction The positive impact of food on health was postulated by the ancient Hippocrates, father of modern medicine with his famous quote: “Let food be thy medicine and medicine be thy food” [1]. In the 21st century, scientists have focused on the effect of nutritional habits in diseases. Nowadays, it is well documented that food plays a noteworthy role in the pathogenesis of chronic diseases namely cardiovascular diseases (CVD), metabolic syndrome, diabetes mellitus type II, and cancer [2–5], as it correlates with others with the lipid pattern, the blood pressure, and the endothelial function. The scientists examine the effect of nutritional habits on disease emergence and progression in both individual nutrient intake and dietary patterns models. Worldwide, two dietary patterns are usually compared—the Mediterranean diet (MD) and the Western diet (WD) [3,6]. The Mediterranean diet reflects the food culture of most Mediterranean countries based on olive oil consumption, seasonal fresh vegetables, cereals, and plants in balance with low consumption of meat [7]. The Western diet, on the contrary, is dominated by high-fat dairy products processed and red meat [8]. However, discordance in the different MD patterns and consumed food doses had been recognized. Without any doubt, those discrepancies could confine and restrict our knowledge on the health benefit mechanisms of the MD [9]. Due to the above, the medical community along with nutritionists and dieticians take a keen interest in MD and its traits [7]. https://www.academia.edu/45378994/biomedicines_Mediterranean_Diet_as_a_Tool_to_Combat_Inflammation_and_Chronic_Diseases_An_Overview?email_work_card=view-paper food choices can fight inflammation and chronic disease Bottom Line: This is a 2020 paper and since then literally hundreds of papers on the MD have emerged showing how the food plan lowers inflammation and the risk for developing multiple chronic illnesses. Even still, lots of research needs to be done to elucidate the many mechanisms of how food impacts our system and how to optimally individualize dietary recommendations. At this point, our best strategy to prevent and/or recover from any chronic condition is to eat as clean and natural as possible. It has become rather obvious that the further away from a natural diet we get, the sicker we become. On top of that, I have yet to see a full recovery from any health issue without the foundation of a predominantly plant-based, unprocessed, whole foods approach…which is why I keep posting about this subject. All the best to you and yours!
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