Covid-19 and Health Update: Dietary Alterations Effective for Migraine

RVAchironeuro • July 22, 2021

Hello Everyone:

This blog related indirectly to Covid-19, as you will see below. I am reporting on new research that reveals that the composition of essential fatty acids (EFA’s) in the diet has a profound influence on migraine frequency and severity. Here are the essentials:

What is already known on this topic

  • Modern industrialized diets tend to be low in n-3 eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and high in n-6 linoleic acid
  • These fatty acids serve as precursors to endogenous signaling molecules (oxylipins) shown to increase (linoleic acid) or decrease (EPA+DHA) pain in preclinical models

What this study adds

  • Adults with chronic and episodic migraine in the United States were randomized to the H3 diet (increased EPA+DHA), the H3-L6 diet (increased EPA+DHA, reduced linoleic acid), or a control diet (average US intake of n-3 and n-6 fatty acids)
  • While the benefit of the H3 and H3-L6 diets on quality of life was inconclusive, the reduction in headaches was robust, particularly for the H3-L6 diet

“This study provides a biologically plausible demonstration that pain can be treated through targeted dietary alterations in humans. Collective findings suggest causal mechanisms linking n-3 and n-6 fatty acids to nociception and open the door to new approaches for managing chronic pain in humans.”

Bottom Line:
In the diet that raised Omega-3 EFA’s and lowered Omega-6’s (the H3-L6 diet),  there was a robust reduction in headache intensity and frequency on par with Botox and medications that lower CGRP (Emgality, Aimovig). This is really something that everyone should be aware of. Why? Because diets high in Omega-6 EFA’s promote inflammation, and this has the potential to cause, perpetuate or aggravate every known human ailment!!

What are sources of Omega-6 to reduce in our diet? Start with lowering or removing ALL processed foods, foods fried in any vegetable oil (chips), canola oil, sunflower oil, soybean oil, corn oil, peanut oil, palm oil etc. The Omega-6’s that we get from whole foods like walnuts, seeds, etc. do not contribute as significantly as processed oils do to inflammation. Once again, the Mediterranean diet will shine in this aspect as it not only has lower processed Omega-6 oils, it also has higher Omega-3’s (fish, flaxseeds, pumpkin seeds, walnuts, chia, hemp hearts etc.). As you might guess, olive oil is super good as it is low in Omega-6’s.

How does this relate to Covid-19? The higher the Omega-6’s, the more background inflammation which results in a more unbalanced immune system leading towards hyper-inflammation during infections. Also, a vital key to resolution of all infections and inflammation are natural derivatives of Omega-3’s called pro-resolving mediators, or resolvins. Being low in resolvins can make is difficult to get over any infection and seeing how research literature reports over 90% of Americans are deficient, it is critical to correct this state and that should start with dietary measures and perhaps supplements as well. For more info, check these links:

 

 

By Mark Smith March 23, 2026
Health News Update: How To Fight Inflammation and Chronic Disease 3.23.26 Hello again everyone: You might wonder why I keep focusing on food…so here are some of the reasons: food choices are the leading cause of death in the U.S. and spreading around the world. Poor food choices lead to inflammation which slowly destroy health. It is that simple, plain, and clear and backed by research. The next question: how do we fight back? Introduction The positive impact of food on health was postulated by the ancient Hippocrates, father of modern medicine with his famous quote: “Let food be thy medicine and medicine be thy food” [1]. In the 21st century, scientists have focused on the effect of nutritional habits in diseases. Nowadays, it is well documented that food plays a noteworthy role in the pathogenesis of chronic diseases namely cardiovascular diseases (CVD), metabolic syndrome, diabetes mellitus type II, and cancer [2–5], as it correlates with others with the lipid pattern, the blood pressure, and the endothelial function. The scientists examine the effect of nutritional habits on disease emergence and progression in both individual nutrient intake and dietary patterns models. Worldwide, two dietary patterns are usually compared—the Mediterranean diet (MD) and the Western diet (WD) [3,6]. The Mediterranean diet reflects the food culture of most Mediterranean countries based on olive oil consumption, seasonal fresh vegetables, cereals, and plants in balance with low consumption of meat [7]. The Western diet, on the contrary, is dominated by high-fat dairy products processed and red meat [8]. However, discordance in the different MD patterns and consumed food doses had been recognized. Without any doubt, those discrepancies could confine and restrict our knowledge on the health benefit mechanisms of the MD [9]. Due to the above, the medical community along with nutritionists and dieticians take a keen interest in MD and its traits [7]. https://www.academia.edu/45378994/biomedicines_Mediterranean_Diet_as_a_Tool_to_Combat_Inflammation_and_Chronic_Diseases_An_Overview?email_work_card=view-paper food choices can fight inflammation and chronic disease Bottom Line: This is a 2020 paper and since then literally hundreds of papers on the MD have emerged showing how the food plan lowers inflammation and the risk for developing multiple chronic illnesses. Even still, lots of research needs to be done to elucidate the many mechanisms of how food impacts our system and how to optimally individualize dietary recommendations. At this point, our best strategy to prevent and/or recover from any chronic condition is to eat as clean and natural as possible. It has become rather obvious that the further away from a natural diet we get, the sicker we become. On top of that, I have yet to see a full recovery from any health issue without the foundation of a predominantly plant-based, unprocessed, whole foods approach…which is why I keep posting about this subject. All the best to you and yours!
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