Health Update: Intermittent Fasting Lowers Inflammation & Boosts Health

Mark Smith • January 29, 2024

Hello again everyone:

 

There continues to be ongoing and robust investigation into the health building effects of intermittent fasting. As the research mounts, the conclusions are similar to those in this study that looked into the inflammatory chemicals that abdominal fat secretes. The article states that our abdominal or visceral fat is considered an endocrine organ that has far reaching health effects related to insulin resistance, weight gain, appetite control, the health of our arteries, immune regulation, fatigue, atherosclerosis, heart health, brain health, and energy metabolism. These effects are mediated or caused by a group of chemicals secreted by our abdominal fat cells and are called adipokines. These adipokines can be anti-inflammatory or pro-inflammatory and their secretion can become dysregulated. This means that in overfed states, insulin resistant, overweight and obese situation, our adipokines are largely inflammatory and destroy our health.

 

Consuming food in patterns in harmony with our natural circadian rhythms is called early Time Restricted Feeding (eTRF), and it is that pattern of intermittent feeding that so far holds the greatest promise for improving long term health. The authors state the following:

 

“Adipose tissue is now recognized as an endocrine organ that secretes bioactive molecules called adipokines. These biomolecules regulate key physiological functions, including insulin sensitivity, energy metabolism, appetite regulation, endothelial function, and immunity. Dysregulated secretion of adipokines is intimately associated with obesity, and translates into increased risk of obesity-related cardiovascular-metabolic diseases.

 

In particular, emerging evidence suggests that adipokine imbalance contributes to the pathogenesis of atherosclerosis. One of the promising diet regimens that is beneficial in the fight against obesity and cardiometabolic disorders is intermittent fasting (IF). Indeed, IF robustly suppresses inflammation, meditates weight loss and mitigates many aspects of the cardiometabolic syndrome…... By exploring a plethora of the beneficial effects of IF, particularly on inflammatory markers, we present IF as a possible intervention to help prevent atherosclerosis.”

 

https://www.sciencedirect.com/science/article/abs/pii/S0006295223004677

 

Bottom Line:

 

 If you have abdominal fat, it is important to recognize that carrying around that type of fat is highly inflammatory and health destroying…and in most cases you cannot even feel the inflammation as it is silently marinating all of your tissues in a destructive stew of inflammatory chemicals. This background inflammation is not the same as what you see when you sprain an ankle, or the redness of a sunburn or the swelling and redness around a cut or scrape…it is the type of inflammation that damages your arteries over years and leads to that fatal or disabling heart attack, or dementia, or brain fog, or fatigue, or headaches, etc.

 

Where can you start??? Once again, I will recommend the following book and companion cookbook to get you started on the right way to do eTRF: “What to Eat When” by Michael Roizen, MD. Start this year by creating a new you by simply adopting easy to do intermittent fasting. This is a super healthy and positive lifestyle upgrade that will give you many possible benefits. Remember, inflammation causes, perpetuates, and aggravates EVERY KNOWN HUMAN AILMENT…a key and essential part of the way to lower your total burden of inflammation is to consume unprocessed, organic, whole foods in an intermittent fasting pattern called early Time Restricted Feeding: Always have some type of breakfast (dinner for breakfast often works very well), get 80% of your total daily calories by 2 PM, and have an early light dinner that comprises only 20% of your total daily caloric load. You can do this and save your own life.

By Mark Smith March 23, 2026
Health News Update: How To Fight Inflammation and Chronic Disease 3.23.26 Hello again everyone: You might wonder why I keep focusing on food…so here are some of the reasons: food choices are the leading cause of death in the U.S. and spreading around the world. Poor food choices lead to inflammation which slowly destroy health. It is that simple, plain, and clear and backed by research. The next question: how do we fight back? Introduction The positive impact of food on health was postulated by the ancient Hippocrates, father of modern medicine with his famous quote: “Let food be thy medicine and medicine be thy food” [1]. In the 21st century, scientists have focused on the effect of nutritional habits in diseases. Nowadays, it is well documented that food plays a noteworthy role in the pathogenesis of chronic diseases namely cardiovascular diseases (CVD), metabolic syndrome, diabetes mellitus type II, and cancer [2–5], as it correlates with others with the lipid pattern, the blood pressure, and the endothelial function. The scientists examine the effect of nutritional habits on disease emergence and progression in both individual nutrient intake and dietary patterns models. Worldwide, two dietary patterns are usually compared—the Mediterranean diet (MD) and the Western diet (WD) [3,6]. The Mediterranean diet reflects the food culture of most Mediterranean countries based on olive oil consumption, seasonal fresh vegetables, cereals, and plants in balance with low consumption of meat [7]. The Western diet, on the contrary, is dominated by high-fat dairy products processed and red meat [8]. However, discordance in the different MD patterns and consumed food doses had been recognized. Without any doubt, those discrepancies could confine and restrict our knowledge on the health benefit mechanisms of the MD [9]. Due to the above, the medical community along with nutritionists and dieticians take a keen interest in MD and its traits [7]. https://www.academia.edu/45378994/biomedicines_Mediterranean_Diet_as_a_Tool_to_Combat_Inflammation_and_Chronic_Diseases_An_Overview?email_work_card=view-paper food choices can fight inflammation and chronic disease Bottom Line: This is a 2020 paper and since then literally hundreds of papers on the MD have emerged showing how the food plan lowers inflammation and the risk for developing multiple chronic illnesses. Even still, lots of research needs to be done to elucidate the many mechanisms of how food impacts our system and how to optimally individualize dietary recommendations. At this point, our best strategy to prevent and/or recover from any chronic condition is to eat as clean and natural as possible. It has become rather obvious that the further away from a natural diet we get, the sicker we become. On top of that, I have yet to see a full recovery from any health issue without the foundation of a predominantly plant-based, unprocessed, whole foods approach…which is why I keep posting about this subject. All the best to you and yours!
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