Health News Update: Fasting, Vegetarian Diet and Autoimmunity

Mark Smith • February 10, 2025

Hello everyone:


Here are a bunch of papers that show that those with Rheumatoid Arthritis can significantly benefit from fasting followed by a vegetarian dietary plan. When it comes to the benefits of fasting, autoimmune disorders have a good deal of evidence backing up the efficacy. Other disorders related to lifestyle factors, such as overweight, obesity, type 2 diabetes, high blood pressure, and digestive issues also tend to show benefits, i.e., anyone with excess inflammation will probably benefit a lot.


“There is clear experimental evidence of a significant anti-inflammatory effect of prolonged fasting. Several clinical studies demonstrated a symptomatic benefit of prolonged modified fasting (therapeutic fasting) in rheumatoid arthritis (RA). If fasting is followed by a vegan and vegetarian diet, lasting effects of up to 1 year have been documented. Cardiometabolic but not antirheumatic effects have been proven for intermittent fasting. Nutrition and fasting can be classified as a possible useful addition to conventional treatment but are currently only rarely taken into account in practice.”

 

https://pubmed.ncbi.nlm.nih.gov/7747149/

 

https://pubmed.ncbi.nlm.nih.gov/1681264/

 

https://pubmed.ncbi.nlm.nih.gov/7835013/

 

https://pubmed.ncbi.nlm.nih.gov/11252685/

 

https://pubmed.ncbi.nlm.nih.gov/39271484/


Bottom Line:

 

The absolute most critical part of this literature is that the positive effects of fasting were only maintained when the post-fasting diet is vegan or vegetarian. This appears to be related in part to different aspects of an omnivorous food plan that alter essential fatty acid imbalances and gut microbiome changes that foster inflammation. There are many different ways to fast, and I always recommend that you start with eTRF (early Time Restricted Feeding) to re-set and normalize your circadian rhythms before moving on to any type of fasting that may be more demanding or rigorous or require medical monitoring. The benefit of eTRF is that you can move into a vegetarian or vegan diet at the same time as you fast daily. Most of the time, consuming your vegetarian/vegan food plan (or even the Flexitarian food plan from Dr. Joel Furhman) in an eTRF pattern is enough to shift your health where you want it to go.


 “Here we show that eTRF was more effective than mTRF (mid-day) at improving insulin sensitivity. Furthermore, eTRF, but not mTRF, improved fasting glucose, reduced total body mass and adiposity, ameliorated inflammation, and increased gut microbial diversity. No serious adverse events were reported during the trial. In conclusion, eTRF showed greater benefits for insulin resistance and related metabolic parameters compared with mTRF.”

 

https://pubmed.ncbi.nlm.nih.gov/35194047/


Essentially, eTRF is having some type of breakfast before 10:00 am and a lunch before 2 pm, and lunch is essentially the largest meal of the day. The main point is to consume 80% of your total daily calories by 2 pm, and dinner is very light and taken early such that you consume all of your daily calories within 10 hours. Eating this way will correct any abnormal circadian rhythm functions (such as blood sugar control, fat burning, digestive issues, and more) and it can take up to 3 to 4 months to reset your internal clocks. If you have not felt better or lost weight, the next step would be to go Flexitarian or Vegan/Vegetarian with eTRF. These food plans are essentially unprocessed, whole-food, plant-based, lower fat, no sugar, no processed grains or foods. In an earlier blog I addressed resources to assist in this amazing transformation so here they are again!


1.      https://simplyplantbasedkitchen.com/

 

2.     https://thriving.foodrevolution.org/join/?frn_source=blog&frn_medium=link&frn_campaign=ppt&frn_content=menu

 

3.     https://hellonutritarian.com/nutritarian-power-prep-program/

 

4.     https://cookingcourse.forksoverknives.com/

 

5.     https://www.drfuhrman.com/blog/210/beginners-guide


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