Covid-19 Update: Vaccine Update

RVAchironeuro • September 14, 2020

Hello again everyone:

  This blog is about the upcoming vaccines and what you need to know. To put things into a proper perspective so that we all have realistic expectations, you should really take the time to read these two articles:

While this second article is pretty long, you will benefit to read it as it is fascinating and gives a really great bunch of insights and overviews of vaccine development history and how that plays into the current pandemic…a nice dose of reality to help make sure we have appropriate expectations is good medicine:

Prtinent Points that you need to be aware of in terms of what it will take to get any vaccine made, analyzed properly, production, distribution, availability, time-line issues:

  • The need to scale up manufacturing capacity to levels never seen before
  • Some vaccines require shipping at below zero temperatures
  • Estimates are that doses will be available for 20% of the global population by the end of next year
  • Distribution capabilities now are far below what will be needed
  • Vaccines cannot be administered to millions of people quickly
  • Administration of vaccines will require qualified & trained people with oversight
  • Accumulating sufficient safety and efficacy data will extend through 2020 and probably into next year, report vaccine experts
  • Deciding who gets the vaccine first (high risk populations), plus this vaccine will require two dosages a month apart (estimated 300 million dosages needed initially)
  • Uncertainty about how many will need to be vaccinated or have had the virus in order to achieve ‘herd immunity’
  • Deciding when the pandemic is over and the virus becomes endemic (like the flu is now) and what to do going forward

Not only that, please read what the vaccine experts say about what to expect:

  Once manufacturing and distribution are complete, Americans would still not be safe from the disease, experts cautioned. The vaccines are unlikely to protect against shedding, Offit said; vaccinated people may still get mild or asymptomatic infections, and thus shed the virus and possibly spread it to others. “People who are vaccinated still need to wear masks and that’s going to be a hard message to send,” Offit said. “You may take a step backwards.”

Said Bar-Zeev: “The community expects this is going to go away when we have a vaccine, and it might not.”

Still, when would we have that vaccine? Aronoff considers the end of 2020 to be “an uphill battle.” He could see a scenario in which the FDA issues an emergency use authorization for use by just one group of at-risk people and a subset of American hospitals, following CDC guidelines.

But: “It’s hard to imagine that that isn’t somewhat just for show,” he said.

Could that happen by Nov. 3? “I hate to say it’s impossible,” Aronoff said. “I’d like to see a safe and effective vaccine sooner rather than later, but it’s really hard for me to imagine large-scale manufacturing and distribution of a vaccine that we know is safe and effective before the end of October.”

It will be important to work with CDC and the World Health Organization, Aronoff said, noting the disease continues to spread globally. In addition, the IFPMA noted that most vaccine production occurs in Europe.

“It’s a perfect storm of issues. We really have to get it right,” Bar-Zeev said. “To use an average product in a sub-optimal way would do a lot of harm.”

Bottom Line: It May Not Be a Good Idea to Put All of Your Eggs in One Basket…that is, waiting for the vaccine may not be your best single strategy… and this simply means that it is still extremely important to become as metabolically healthy as possible to reduce your risk of infection as well as possibly lowering the severity and duration. And because of the roll-out time until a vaccine becomes available, it means that you STILL HAVE TIME to create a lifestyle that improves your overall metabolic health…which, by the way, may help increase the efficacy of a vaccine. Using a quote from the above link to the New Yorker article:

There are lots of ways to fight back against SARS-CoV-2 and COVID-19, the disease it causes. We can limit the virus’s spread in the population at large; we can also build barriers against infection for at-risk people, such as caregivers or essential workers, in particular. We can devise therapies that prevent the newly infected from getting worse, and we can create interventions that target the sickest and give them a fighting chance. By surrounding the virus in this way, we can make it less contagious and lethal, changing the character of the pandemic.”

In my opinion, the available science strongly supports that “surrounding the virus” should include Vitamin D, Zinc and Vitamin C, avoiding processed foods and sugar, daily exercise, good sleep habits, as well as all of the other strategies for improving immune resilience and overall health that we have gone over in my previous blogs. Making these efforts can offset some of the fear and anxiety associated with this temporary chaos/uncertainty.

  We simply need to use all of the tools in the toolbox…from vaccines to vitamins…so now is the time to seriously upgrade your health as we can use this pandemic as an opportunity to jump start our return to optimal form, both as individuals and as a country.

Keep Calm…and Get Healthy!

By Mark Smith April 27, 2026
Health New Update: Millions of Lives Saved by Healthy Eating 4.27.26 Hey everyone: Here is some research that reveals that healthy eating could save millions of lives every year and also improve economics and planetary health. Wow!! They analyzed 3 different types of diets, and all of them are a significant improvement compared to the Standard American Diet, and this study looked at worldwide diets. The different diet scenarios were implemented by adjusting the region-specific diets described in the reference scenario, which maintained the regional character of food consumption. The HGD (Healthy Global Diet) diet included (per day) a minimum of five portions of fruits and vegetables, fewer than 50 g of sugar, a maximum of 43 g of red meat (the size of a small deck of cards), and an energy content of 2,200–2,300 kcal, depending on the age and sex composition of the population. The VGT (Vegetarian)and VGN (Vegan) diets differed from the HGD in including six (VGT) or seven (VGN) portions of fruits and vegetables and one portion of pulses, with no red meat, poultry, or fish, and in the VGN diet no dairy or eggs. What did they find? Moving to diets with fewer animal-sourced foods would have major health benefits ( Fig. 1A ). Compared with the reference scenario, we project that adoption of global dietary guidelines (HGD) would result in 5.1 million avoided deaths per year [95% confidence interval (CI), 4.8–5.5 million] and 79 million years of life saved (CI, 75–83 million) ( Fig. 1A and SI Appendix, Fig. S2 ). The equivalent figures for the vegetarian (VGT) diet are 7.3 million avoided deaths (CI, 7.0–7.6 million) and 114 million life years saved (CI, 111–118 million) and for the vegan (VGN) diet 8.1 million avoided deaths (CI, 7.8–8.5 million) and 129 million life years saved (CI, 125–133 million). Differentiated by risk factor, more than half of avoided deaths (51–57% across the three scenarios) were due to decreased red meat consumption, 24–35% to increased fruit and vegetable consumption, and 19–30% to a lower prevalence of being overweight and obese associated with limiting excessive energy intake. The reduced mortality in the VGT and VGN scenarios compared with the HGD scenario was due to lower red meat consumption (1.7 million additional avoided deaths in each) and higher fruit and vegetable consumption (VGT, 0.8 million; VGN, 1.8 million additional avoided deaths). Across the three nonreference scenarios, about 45–47% of all avoided deaths were from reduced coronary heart disease (CHD), 26% from stroke, 16–18% from cancer, and 10–12% from type 2 diabetes mellitus (T2DM) https://pmc.ncbi.nlm.nih.gov/articles/PMC4839446/ Healthy eating saves millions Bottom Line: By eating better, millions of lives could be saved. Please read the above paragraph again slowly as it is a lot to take in. Now ask yourself: is my diet optimal? If I can reduce my risk of chronic disease, extend both my health and life span, what am I waiting for?
By Mark Smith April 20, 2026
Health News Update: What to Eat and Longevity 4.20.26 Hello again: It is important to note that in our society we are living longer but sicker. The current lifestyle our country offers is not creating a healthy population, but it is supporting medically managed sick people. It seems to me that the optimal strategy would be to combine our traditional medical care with a lifestyle that supports health promotion and longevity. To that end, food is a powerful tool…more powerful than we are told. Here is what this study looked at: “As the global population ages, it is critical to identify diets that, beyond preventing noncommunicable diseases, optimally promote healthy aging. Here, using longitudinal questionnaire data from the Nurses’ Health Study (1986–2016) and the Health Professionals Follow-Up Study (1986–2016), we examined the association of long-term adherence to eight dietary patterns and ultraprocessed food consumption with healthy aging, as assessed according to measures of cognitive, physical and mental health, as well as living to 70 years of age free of chronic diseases.” And here is what they found: “Higher intakes of fruits, vegetables, whole grains, unsaturated fats, nuts, legumes and low-fat dairy products were linked to greater odds of healthy aging, whereas higher intakes of trans fats, sodium, sugary beverages and red or processed meats (or both) were inversely associated. Our findings suggest that dietary patterns rich in plant-based foods, with moderate inclusion of healthy animal-based foods, may enhance overall healthy aging, guiding future dietary guidelines.” https://www.nature.com/articles/s41591-025-03570-5 Optimal dietary patterns for longevity. Bottom Line: What this means is switching to the Green Mediterranean dietary food plan is the way to go to optimize your health span and life span while avoiding or minimizing chronic disease risk. If you simply consume unprocessed to minimally processed whole foods, eat predominantly vegetables, fruits, nuts, seeds, whole grains, beans and avoid processed foods, added sugars, and refined grains. Just avoiding the Standard American Diet (SAD) would result in tremendous improvement in the health of our nation and the world. I offer this information for several reasons: · I have not seen anyone recover their health eating a poor diet. · Research has shown that food is the leading cause of death and disability. · No one else can do this for you. · You can literally save your own life with your fork and spoon. · Everything I just said is true and applies to everyone. · There is literally no good reason not to eat as good as you can. 
By Mark Smith April 13, 2026
Health News Update: When to Eat Really Matters 4.13.26 Hello everyone: You have probably heard of the old saying recommending eating breakfast like a king or queen, lunch like a prince/princess, and dinner like a pauper. It turns out that new studies are revealing that meal timing is critical for long term health. “At the study’s conclusion, researchers found that participants following early and mid-day time-restricted eating experienced better outcomes, including a lowering of body weight , waist circumference , body mass index (BMI) , fat mass , systolic blood pressure , and fasting glucose ( blood sugar ) levels, when compared to participants who ate late in the day. “These findings highlight that aligning food intake earlier in the day, when metabolic processes such as insulin sensitivity are more favorable, may amplify the benefits of time-restricted eating,” Chen explained. “The results suggest that not all time-restricted eating patterns are equal. Eating earlier appears to confer broader metabolic advantages compared with delaying food intake to later hours,” he added. Additionally, scientists discovered that late-day eating, when combined with a longer eating window, was the least effective dietary pattern for the most metabolic benefits. https://www.medicalnewstoday.com/articles/time-restricted-eating-early-window-best-metabolism?utm_source=ReadNext#Time-restricted-eating-Time-of-day-and-eating-window-size When you eat really matters Bottom Line: Your biology always works best when it is running in time with your natural circadian rhythms. One of the things that can alter your circadian clocks and lead to problems is when we eat and how much, plus the quality of the food. Making sure you align your food intake with your body clock is an important aspect of health and is considered a modifiable risk factor. In other words, it is best to eat in concordance with your own biological rhythms. Will this work for everyone? Probably not, but some form of intermittent fasting will work which means experiment with this concept to find the best clock management that works for you. For example, breakfast like a prince or princess, lunch like a king or queen, dinner like a pauper. The important keys are to have some kind of breakfast and have dinner be the smallest meal of the day as early as possible. To find out more how meal timing can promote health, check out these terms: Circadian autophagy.
By Mark Smith April 6, 2026
Health News Update: Sleep Timing, Mood & Performance 4.6.26 Hello everyone: In taking a history at the start of a healthcare process, I often find people of all ages have sleep schedules that do not match optimal circadian rhythms and have un-knowingly contributed to degrading their health. Sleep is a significant component of leading an anti-inflammatory lifestyle as it fosters autophagy (an immune based essential self-cleaning function, hormonal regulation, stress reduction, immune resilience, optimal aging, and more. As it turns out, getting your sleep timing right lowers depression, reduces morning fatigue, improves physical functions, and can markedly increase your ability to think, recall things and overall cognitive functions. Proper sleep timing aligned with our natural circadian clocks may also decrease mortality risks. Background There is conflict between living according to our endogenous biological rhythms and our external environment, with disruptions resulting in negative consequences to health and performance. This is often documented in shift work and jet lag , but ‘societal norms’ (eg, typical working hours) can create profound issues for ‘night owls’, people whose internal biological timing predisposes them to follow an unusually late sleep-wake cycle. Night owls have also been associated with health issues, mood disturbances, poorer performance and increased mortality rates . Results Overall, participants demonstrated a significant advance of ∼2 h in sleep/wake timings as measured by actigraphy and circadian phase markers (dim light melatonin onset and peak time of the cortisol awakening response), whilst having no adverse effect on sleep duration. Notably, the phase advance was accompanied by significant improvements to self-reported depression and stress, as well as improved cognitive (reaction time) and physical (grip strength) performance measures during the typical ‘suboptimal’ morning hours. https://www.sciencedirect.com/science/article/abs/pii/S1389945719301388?via%3Dihub resetting sleep timing improves brain function and overall health. Bottom Line: For long term health, assisting recovery, optimal aging, improving immune resilience, lowering your total inflammatory burden thus reducing your risk for developing chronic diseases…it looks like a very good idea to get your sleep cycles in line with your natural biological rhythms. The researchers aimed to accomplish this using only simple practical natural lifestyle methods…no medications. Here is some of what they did: · Avoid blue light after dark. · Get some early morning sunshine…even 5 minutes will help. · Exercise in the morning or early afternoon. · Adopt early time restricted feeding schedules (eTRF). · Fix a time to sleep and stick to it. If you have any chronic health issues, or just want to optimize the aging process, simply adopt a few simple lifestyle strategies. I have seen this clinically be one of the major keys to the success when it comes to overcoming fatigue, brain fog, digestive issues, and any chronic health problem. Best wishes to you for a healthy life!
By Mark Smith March 30, 2026
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By Mark Smith March 23, 2026
Health News Update: How To Fight Inflammation and Chronic Disease 3.23.26 Hello again everyone: You might wonder why I keep focusing on food…so here are some of the reasons: food choices are the leading cause of death in the U.S. and spreading around the world. Poor food choices lead to inflammation which slowly destroy health. It is that simple, plain, and clear and backed by research. The next question: how do we fight back? Introduction The positive impact of food on health was postulated by the ancient Hippocrates, father of modern medicine with his famous quote: “Let food be thy medicine and medicine be thy food” [1]. In the 21st century, scientists have focused on the effect of nutritional habits in diseases. Nowadays, it is well documented that food plays a noteworthy role in the pathogenesis of chronic diseases namely cardiovascular diseases (CVD), metabolic syndrome, diabetes mellitus type II, and cancer [2–5], as it correlates with others with the lipid pattern, the blood pressure, and the endothelial function. The scientists examine the effect of nutritional habits on disease emergence and progression in both individual nutrient intake and dietary patterns models. Worldwide, two dietary patterns are usually compared—the Mediterranean diet (MD) and the Western diet (WD) [3,6]. The Mediterranean diet reflects the food culture of most Mediterranean countries based on olive oil consumption, seasonal fresh vegetables, cereals, and plants in balance with low consumption of meat [7]. The Western diet, on the contrary, is dominated by high-fat dairy products processed and red meat [8]. However, discordance in the different MD patterns and consumed food doses had been recognized. Without any doubt, those discrepancies could confine and restrict our knowledge on the health benefit mechanisms of the MD [9]. Due to the above, the medical community along with nutritionists and dieticians take a keen interest in MD and its traits [7]. https://www.academia.edu/45378994/biomedicines_Mediterranean_Diet_as_a_Tool_to_Combat_Inflammation_and_Chronic_Diseases_An_Overview?email_work_card=view-paper food choices can fight inflammation and chronic disease Bottom Line: This is a 2020 paper and since then literally hundreds of papers on the MD have emerged showing how the food plan lowers inflammation and the risk for developing multiple chronic illnesses. Even still, lots of research needs to be done to elucidate the many mechanisms of how food impacts our system and how to optimally individualize dietary recommendations. At this point, our best strategy to prevent and/or recover from any chronic condition is to eat as clean and natural as possible. It has become rather obvious that the further away from a natural diet we get, the sicker we become. On top of that, I have yet to see a full recovery from any health issue without the foundation of a predominantly plant-based, unprocessed, whole foods approach…which is why I keep posting about this subject. All the best to you and yours!
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